Blar i forfatter "Schanche, Torstein"

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    • Maintaining intravenous volume mitigates hypothermia-induced myocardial dysfunction and accumulation of intracellular Ca2+ 

      Nilsen, Jan Harald; Schanche, Torstein; Kondratiev, Timofei V.; Hevrøy, Olav; Tveita, Torkjel; Sieck, Gary C. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-17)
      Previous research exploring pathophysiological mechanisms underlying circulatory collapse after rewarming victims of severe accidental hypothermia has documented post-hypothermic cardiac dysfunction and hypothermia-induced elevation of intracellular Ca<sup>2+</sup> concentration ([Ca<sup>2+</sup>]<sub>i</sub>) in myocardial cells. The aim of the present study was to examine if maintaining euvolaemia ...

    • Rewarming With Closed Thoracic Lavage Following 3-h CPR at 27°C Failed to Reestablish a Perfusing Rhythm 

      Nivfors, Joar O.; Mohyuddin, Rizwan; Schanche, Torstein; Nilsen, Jan Harald; Valkov, Sergei; Kondratiev, Timofei V.; Sieck, Gary C.; Tveita, Torkjel (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-29)
      Introduction: Previously, we showed that the cardiopulmonary resuscitation (CPR) for hypothermic cardiac arrest (HCA) maintained cardiac output (CO) and mean arterial pressure (MAP) to the same reduced level during normothermia (38°C) vs. hypothermia (27°C). In addition, at 27°C, the CPR for 3-h provided global O2 delivery (DO2) to support aerobic metabolism. The present study investigated if rewarming ...